Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20026408 | 1.00 | STING1 (0.43) | STING1PPARG | |
| SCHEMBL21884176 | 1.00 | STING1 (0.43) | STING1PPARG | |
| SCHEMBL8970110 | 0.85 | STING1 (0.33) | STING1PPARG | |
| SCHEMBL14032017 | 0.82 | STING1 (0.48) | STING1 | |
| SCHEMBL22291689 | 0.82 | STING1 (0.48) | STING1 | |
| SCHEMBL26502255 | 0.81 | STING1 (0.33) | STING1PPARG | |
| SCHEMBL21347702 | 0.80 | STING1 (0.41) | STING1 | |
| SCHEMBL2761304 | 0.78 | KMT2A (0.39) | STING1 | |
| SCHEMBL2761303 | 0.78 | KMT2A (0.39) | STING1 | |
| SCHEMBL20022170 | 0.77 | STING1 (0.32) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730849-B2 | Benzo[b]thiophene compounds as STING agonists | MERCK SHARP & DOHME CORP. (US) | 2020-08-04 | — | — | US | disclosed |
| US-10703738-B2 | Benzo[b]thiophene compounds as STING agonists | MERCK SHARP & DOHME CORP. (US) | 2020-07-07 | — | — | US | disclosed |
| US-20190337917-A1 | BENZO[b]THIOPHENE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2019-11-07 | — | — | US | disclosed |
| WO-2019195124-A1 | BENZOTHIOPHENES AND RELATED COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2019-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730849-B2 | Benzo[b]thiophene compounds as STING agonists | STING1, IRF3, CGAS | STING1 1/4885PPARG 1338/4885 |
| US-20190337917-A1 | BENZO[b]THIOPHENE COMPOUNDS AS STING AGONISTS | STING1, IRF3, CGAS | STING1 1/4885PPARG 1338/4885 |
| US-10703738-B2 | Benzo[b]thiophene compounds as STING agonists | STING1, IRF3, CGAS | STING1 1/4885PPARG 1338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.