Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 17/20 | 0.80 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22200642 | 0.95 | STING1 (0.80) | STING1ACHE | |
| SCHEMBL20022244 | 0.90 | STING1 (0.80) | STING1 | |
| SCHEMBL20022194 | 0.90 | STING1 (0.76) | STING1ACHE | |
| SCHEMBL21405886 | 0.89 | STING1 (0.79) | STING1ACHE | |
| SCHEMBL20022243 | 0.89 | STING1 (1.00) | STING1ACHE | |
| SCHEMBL21452861 | 0.88 | STING1 (0.77) | STING1ACHE | |
| SCHEMBL21406507 | 0.88 | STING1 (0.82) | STING1ACHE | |
| SCHEMBL21405828 | 0.85 | STING1 (0.65) | STING1ACHE | |
| SCHEMBL30416808 | 0.85 | STING1 (0.65) | STING1ACHE | |
| SCHEMBL21437030 | 0.85 | STING1 (0.79) | STING1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195124-A1 | BENZOTHIOPHENES AND RELATED COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2019-10-10 | — | — | WO | disclosed |