Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 4/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | CCNC | P24863 | 2/20 | 0.37 |
| ▸ | CDK8 | P49336 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21452717 | 1.00 | SSTR1 (0.41) | SSTR1SSTR4CHRM2CHRM5CHRM1 | |
| SCHEMBL21433940 | 1.00 | SSTR1 (0.41) | SSTR1SSTR4CHRM2CHRM5CHRM1 | |
| SCHEMBL21452391 | 1.00 | SSTR1 (0.41) | SSTR1SSTR4CHRM2CHRM5CHRM1 | |
| SCHEMBL21433939 | 1.00 | SSTR1 (0.41) | SSTR1SSTR4CHRM2CHRM5CHRM1 | |
| SCHEMBL21434042 | 1.00 | SSTR1 (0.41) | SSTR1SSTR4CHRM2CHRM5CHRM1 | |
| SCHEMBL21433945 | 0.91 | ABL1 (0.38) | CHRM2CHRM5CHRM1CHRM3PDE2A | |
| SCHEMBL21452611 | 0.91 | SSTR4 (0.42) | SSTR1SSTR4CHRM2CHRM5CHRM1 | |
| SCHEMBL21433976 | 0.91 | SSTR4 (0.42) | SSTR1SSTR4CHRM2CHRM5CHRM1 | |
| SCHEMBL21433941 | 0.91 | ABL1 (0.38) | CHRM2CHRM5CHRM1CHRM3PDE2A | |
| SCHEMBL21452643 | 0.91 | ABL1 (0.38) | CHRM2CHRM5CHRM1CHRM3PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019193516-A2 | SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-10-10 | — | — | WO | disclosed |