SCHEMBL21453528

SCHEMBL21453528

c1ccc(N2c3ccccc3C3(c4ccccc42)c2ccccc2N(c2ccc4c5cccc6c7ccccc7n(c4c2)c65)c2ccccc23)cc1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.33
▸ ATM Q13315 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ MEN1 O00255 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ POLB P06746 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ HTT P42858 1/20 0.32
▸ KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21453527 0.92 KDM4E (0.33) KDM4EATML3MBTL1MEN1ALDH1A1
SCHEMBL20689950 0.91 KDM4E (0.32) KDM4EATML3MBTL1MEN1ALDH1A1
SCHEMBL22751626 0.91 KDM4E (0.32) KDM4EMEN1ALDH1A1POLBMAPT
SCHEMBL22751627 0.91 KDM4E (0.32) KDM4EMEN1ALDH1A1POLBMAPT
SCHEMBL22751628 0.88 — —
SCHEMBL21453524 0.87 KDM4E (0.36) KDM4EATML3MBTL1ALDH1A1
SCHEMBL20689946 0.85 KDM4E (0.35) KDM4EATML3MBTL1ALDH1A1
SCHEMBL21453954 0.85 KDM4E (0.33) KDM4EATML3MBTL1MEN1ALDH1A1
SCHEMBL22751657 0.84 KDM4E (0.32) KDM4EMEN1ALDH1A1POLBMAPT
SCHEMBL22751672 0.84 KDM4E (0.32) KDM4EMEN1ALDH1A1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3978495-B1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO LTD (KR) 2023-05-10 — — EP disclosed
US-20190312210-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-10-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190312210-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLCO4C1, SLCO2A1, SLCO1A2 KDM4E 3411/4885ATM 3884/4885L3MBTL1 2377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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