SCHEMBL21453580

SCHEMBL21453580

c1ccc2c(c1)c1ccccc1c1cc(-c3ccc4c(c3)c3cccc5c6ccccc6c6ccccc6c6ccccc6n4c53)ccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.41
MAPT P10636 4/20 0.41
MEN1 O00255 3/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 3/20 0.41
HTT P42858 3/20 0.41
KMT2A Q03164 3/20 0.41
POLB P06746 2/20 0.41
ALKBH5 Q6P6C2 1/20 0.37
FTO Q9C0B1 1/20 0.37
TSPO P30536 4/20 0.37
HSD17B10 Q99714 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NPY5R Q15761 2/20 0.34
MAPK1 P28482 1/20 0.33
HBB P68871 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
GPR3 P46089 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22858117 1.00 KDM4E (0.41) KDM4EMAPTMEN1ALDH1A1HPGD
SCHEMBL17994993 0.97 KDM4E (0.39) KDM4EMAPTMEN1ALDH1A1HPGD
SCHEMBL21453578 0.97 KDM4E (0.39) KDM4EMAPTMEN1ALDH1A1HPGD
SCHEMBL17995383 0.97 KDM4E (0.39) KDM4EMAPTMEN1ALDH1A1HPGD
SCHEMBL10153530 0.94 KDM4E (0.44) KDM4EMAPTMEN1ALDH1A1HPGD
SCHEMBL16621739 0.94 KDM4E (0.44) KDM4EMAPTMEN1ALDH1A1HPGD
SCHEMBL16621716 0.94 KDM4E (0.37) KDM4EMAPTMEN1ALDH1A1HPGD
SCHEMBL16621732 0.94 KDM4E (0.37) KDM4EMAPTMEN1ALDH1A1HPGD
SCHEMBL23823559 0.93 KDM4E (0.41) KDM4EMAPTMEN1ALDH1A1HPGD
SCHEMBL17994985 0.93 POLB (0.41) KDM4EMAPTMEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038121-B2 9 membered ring carbazole compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-06-15 US disclosed
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2019-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11038121-B2 9 membered ring carbazole compounds SLC25A21, OCIAD2, OXA1L KDM4E 3723/4885MAPT 2041/4885MEN1 4538/4885
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS SLC25A21, OCIAD2, OXA1L KDM4E 3723/4885MAPT 2041/4885MEN1 4538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.