SCHEMBL21454074

SCHEMBL21454074

c1ccc(-c2ccc(-c3cc(-c4ccc5c(c4)c4cccc6c7cccc8sc9cccc(c%10ccccc%10n5c64)c9c87)nc(-c4ccccc4)n3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.39
KMT2A Q03164 7/20 0.39
HPGD P15428 6/20 0.39
MAPT P10636 6/20 0.39
ALDH1A1 P00352 5/20 0.39
KDM4E B2RXH2 4/20 0.39
LMNA P02545 4/20 0.39
GLA P06280 1/20 0.39
NTSR1 P30989 1/20 0.37
PTGES O14684 1/20 0.34
MAOB P27338 3/20 0.33
MAOA P21397 2/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
CYP2C19 P33261 1/20 0.32
NPY5R Q15761 1/20 0.31
HSD17B10 Q99714 2/20 0.31
TSHR P16473 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21454070 0.99 MEN1 (0.40) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL21454075 0.97 MEN1 (0.36) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL21453630 0.96 MEN1 (0.38) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL21453626 0.95 MEN1 (0.38) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL21453799 0.94 MEN1 (0.36) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL21454089 0.93 MEN1 (0.37) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL21453627 0.93 MEN1 (0.34) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL21453788 0.92 KDM4E (0.33) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL21453790 0.91 KDM4E (0.33) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL21453802 0.91 MEN1 (0.33) MEN1KMT2AHPGDMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038121-B2 9 membered ring carbazole compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-06-15 US disclosed
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2019-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11038121-B2 9 membered ring carbazole compounds SLC25A21, OCIAD2, OXA1L MEN1 4538/4885KMT2A 4192/4885HPGD 830/4885
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS SLC25A21, OCIAD2, OXA1L MEN1 4538/4885KMT2A 4192/4885HPGD 830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.