Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 19/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21454846 | 0.89 | STING1 (0.50) | STING1 | |
| SCHEMBL21454815 | 0.87 | STING1 (0.51) | STING1 | |
| SCHEMBL21437395 | 0.84 | STING1 (0.54) | STING1 | |
| SCHEMBL21437314 | 0.79 | STING1 (0.58) | STING1 | |
| SCHEMBL30416399 | 0.78 | STING1 (0.58) | STING1 | |
| SCHEMBL21406360 | 0.78 | STING1 (0.58) | STING1 | |
| SCHEMBL21438284 | 0.76 | STING1 (0.60) | STING1 | |
| SCHEMBL21437127 | 0.75 | STING1 (0.62) | STING1 | |
| SCHEMBL21405764 | 0.75 | STING1 (0.59) | STING1 | |
| SCHEMBL30416824 | 0.75 | STING1 (0.59) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195063-A1 | AZA-BENZOTHIOPHENE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2019-10-10 | — | — | WO | disclosed |