Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24412963 | 0.75 | MAPK1 (0.39) | MAPK1 | |
| SCHEMBL22648979 | 0.74 | MAPK1 (0.43) | MAPK1 | |
| SCHEMBL16001413 | 0.68 | MAPK1 (0.50) | MAPK1 | |
| SCHEMBL16001414 | 0.68 | MAPK1 (0.50) | MAPK1 | |
| SCHEMBL16001412 | 0.68 | MAPK1 (0.50) | MAPK1 | |
| SCHEMBL20118684 | 0.67 | TDP1 (0.39) | — | |
| SCHEMBL22031386 | 0.66 | MAPK1 (0.42) | MAPK1 | |
| SCHEMBL12978409 | 0.66 | MAPK1 (0.42) | MAPK1 | |
| SCHEMBL25589910 | 0.64 | MAPK1 (0.41) | MAPK1 | |
| SCHEMBL12937012 | 0.63 | MAPK1 (0.50) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022229150-A1 | SIRNA TARGETING TMPRSS6 FOR THE TREAWTMENT OF MYELOPROLIFERATIVE DISORDERS | SILENCE THERAPEUTICS GMBH (DE) | 2022-11-03 | — | — | WO | disclosed |
| WO-2019193144-A1 | siRNAs WITH VINYLPHOSPHONATE AT THE 5' END OF THE ANTISENSE STRAND | SILENCE THERAPEUTICS GMBH (DE) | 2019-10-10 | — | — | WO | disclosed |