SCHEMBL21457569

SCHEMBL21457569

CCOC(=O)C=C(C#N)c1ccc(C(=O)O)cc1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.49
TDP1 Q9NUW8 2/20 0.46
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 2/20 0.40
PLA2G4B P0C869 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
PTPN7 P35236 1/20 0.38
PTPN12 Q05209 1/20 0.38
PTPN22 Q9Y2R2 1/20 0.38
POLB P06746 1/20 0.38
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31467360 0.89 SMN1; SMN2 (0.60) SMN1; SMN2KMT2AALDH1A1NPSR1POLB
SCHEMBL9467707 0.89 SMN1; SMN2 (0.60) SMN1; SMN2KMT2AALDH1A1NPSR1POLB
SCHEMBL1054908 0.89 SMN1; SMN2 (0.60) SMN1; SMN2KMT2AALDH1A1NPSR1POLB
SCHEMBL10974068 0.89 SMN1; SMN2 (0.47) SMN1; SMN2TDP1KMT2AALDH1A1NPSR1
Ethane SCHEMBL28319082 0.88 SMN1; SMN2 (0.59) SMN1; SMN2KMT2AALDH1A1NPSR1POLB
SCHEMBL21457257 0.88 ESR1 (0.51) SMN1; SMN2TDP1ALDH1A1NPSR1LMNA
SCHEMBL2581993 0.87 SMN1; SMN2 (0.52) SMN1; SMN2KMT2AALDH1A1POLBMEN1
SCHEMBL23866743 0.87 KMT2A (0.46) SMN1; SMN2TDP1KMT2AALDH1A1NPSR1
SCHEMBL21457707 0.87 SMN1; SMN2 (0.45) SMN1; SMN2TDP1KMT2AALDH1A1NPSR1
SCHEMBL21457501 0.87 KMT2A (0.46) SMN1; SMN2TDP1KMT2AALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117192672-A Resin film, method for producing resin film, and method for producing phase difference film 日东电工株式会社 2023-12-08 CN disclosed
CN-117192671-A Polarizing plate with phase difference layer 日东电工株式会社 2023-12-08 CN disclosed
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
CN-110248971-B Copolymer and optical film using the same 东曹株式会社 2021-11-02 CN disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed