SCHEMBL21457596

SCHEMBL21457596

CCCOC(=O)C(C#N)=Cc1cccc(O)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.62
MAPT P10636 4/20 0.62
PDCD1 Q15116 1/20 0.62
CD274 Q9NZQ7 1/20 0.62
DNM1 Q05193 3/20 0.60
ALDH1A1 P00352 5/20 0.57
KMT2A Q03164 4/20 0.57
LMNA P02545 1/20 0.57
MIF P14174 1/20 0.54
MEN1 O00255 3/20 0.53
PKM P14618 1/20 0.52
HTT P42858 1/20 0.52
PTP4A1 Q93096 1/20 0.51
RECQL P46063 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
HPGD P15428 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457592 1.00 KDM4E (0.62) KDM4EMAPTPDCD1CD274DNM1
SCHEMBL21457247 0.89 MAPT (0.76) KDM4EMAPTPDCD1CD274DNM1
SCHEMBL21457249 0.89 MAPT (0.76) KDM4EMAPTPDCD1CD274DNM1
SCHEMBL21457338 0.88 MAPT (0.64) KDM4EMAPTPDCD1CD274DNM1
SCHEMBL21457342 0.88 MAPT (0.64) KDM4EMAPTPDCD1CD274DNM1
SCHEMBL21457541 0.87 PDCD1 (0.81) KDM4EMAPTPDCD1CD274DNM1
SCHEMBL21457123 0.87 MAPT (0.59) KDM4EMAPTPDCD1CD274DNM1
SCHEMBL21457126 0.87 MAPT (0.81) KDM4EMAPTPDCD1CD274DNM1
SCHEMBL21457121 0.87 MAPT (0.59) KDM4EMAPTPDCD1CD274DNM1
SCHEMBL21457124 0.87 MAPT (0.81) KDM4EMAPTPDCD1CD274DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
CN-110248971-B Copolymer and optical film using the same 东曹株式会社 2021-11-02 CN disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed