Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29988385 | 0.88 | TLR7 (0.39) | L3MBTL1TSHRCYP3A4ALOX15MAPK1 | |
| SCHEMBL146804 | 0.88 | TLR7 (0.39) | L3MBTL1TSHRCYP3A4ALOX15MAPK1 | |
| SCHEMBL14866402 | 0.82 | TLR7 (0.37) | TSHRCYP3A4ALOX15MAPK1PIM1 | |
| SCHEMBL12245244 | 0.76 | PIM1 (0.37) | TSHRCYP3A4ALOX15PIM1LMNA | |
| SCHEMBL30448090 | 0.75 | TLR7 (0.39) | TSHRPIM1LMNACASP1SMN1; SMN2 | |
| SCHEMBL143565 | 0.75 | TLR7 (0.39) | TSHRPIM1LMNACASP1SMN1; SMN2 | |
| SCHEMBL12245205 | 0.75 | TLR7 (0.38) | TSHRCYP3A4ALOX15MAPK1PIM1 | |
| SCHEMBL3251879 | 0.74 | TLR7 (0.39) | L3MBTL1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12245236 | 0.73 | TLR7 (0.36) | L3MBTL1TSHRPIM1NPC1RAB9A | |
| SCHEMBL31092872 | 0.73 | TLR7 (0.51) | LMNAPDE4DTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190314483-A1 | Vaccines Including Antigen From Four Strains of Influenza Virus | SEQIRUS UK LTD (GB) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190314483-A1 | Vaccines Including Antigen From Four Strains of Influenza Virus | LY96, HLA-B, HAVCR2 | L3MBTL1 672/4885TSHR 2999/4885CYP3A4 1812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.