⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20095462 | 1.00 | — | — | |
| SCHEMBL20095399 | 0.94 | — | — | |
| SCHEMBL21462026 | 0.94 | — | — | |
| SCHEMBL21471155 | 0.93 | — | — | |
| SCHEMBL21462024 | 0.90 | — | — | |
| SCHEMBL20095474 | 0.90 | — | — | |
| SCHEMBL20095453 | 0.88 | — | — | |
| SCHEMBL21461999 | 0.83 | — | — | |
| SCHEMBL20095654 | 0.83 | — | — | |
| SCHEMBL20095401 | 0.80 | NAMPT (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11638762-B2 | Targeted delivery of nicotinamide adenine dinucleotide salvage pathway inhibitors | SEAGEN INC. (US) | 2023-05-02 | — | — | US | disclosed |
| US-20190314519-A1 | TARGETED DELIVERY OF NICOTINAMIDE ADENINE DINUCLEOTIDE SALVAGE PATHWAY INHIBITORS | SEATTLE GENETICS, INC. (US) | 2019-10-17 | — | — | US | disclosed |