Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2146687 | 0.90 | PPARA (0.34) | S1PR1MAPTMEN1KMT2ACETP | |
| SCHEMBL2146715 | 0.90 | S1PR1 (0.40) | S1PR1MAPTMEN1KMT2ATP53 | |
| SCHEMBL2146320 | 0.89 | S1PR1 (0.50) | S1PR1MAPTMEN1KMT2ACETP | |
| SCHEMBL2146623 | 0.89 | S1PR1 (0.39) | S1PR1TDP1MAPTMEN1KMT2A | |
| SCHEMBL14798435 | 0.87 | S1PR1 (0.55) | S1PR1MAPTMEN1KMT2ACETP | |
| SCHEMBL2146707 | 0.86 | S1PR1 (0.38) | S1PR1TDP1MAPTMEN1KMT2A | |
| SCHEMBL2146481 | 0.84 | S1PR1 (0.33) | S1PR1MAPTMEN1KMT2ATP53 | |
| SCHEMBL2148943 | 0.82 | SMN1; SMN2 (0.34) | S1PR1MAPTSMN1; SMN2KDM4EPPARG | |
| SCHEMBL2146681 | 0.81 | NPSR1 (0.34) | S1PR1MAPTMEN1KMT2ACETP | |
| SCHEMBL15764405 | 0.80 | S1PR1 (0.57) | S1PR1CETPTP53KDM4EPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523958-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011086077-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |