Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFB | P00751 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2146649 | 1.00 | CFB (0.32) | CFBADRA2CKCNH2 | |
| SCHEMBL18349433 | 0.83 | HTT (0.31) | — | |
| SCHEMBL890073 | 0.83 | HTT (0.31) | — | |
| SCHEMBL18349457 | 0.80 | — | — | |
| SCHEMBL1440132 | 0.78 | — | — | |
| SCHEMBL5795232 | 0.77 | — | — | |
| SCHEMBL18349445 | 0.76 | GBA2 (0.30) | — | |
| SCHEMBL18349463 | 0.75 | — | — | |
| SCHEMBL23060724 | 0.75 | GAA (0.35) | CFBADRA2CKCNH2 | |
| SCHEMBL21908558 | 0.75 | GAA (0.35) | CFBADRA2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088045-A1 | AURORA KINASE COMPOUNDS AND METHODS OF THEIR USE | AMBIT BIOSCIENCES CORPORATION (US) | 2011-07-21 | — | — | WO | disclosed |