Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 17/20 | 0.52 |
| ▸ | PRKDC | P78527 | 17/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 16/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 16/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 16/20 | 0.52 |
| ▸ | ABL1 | P00519 | 11/20 | 0.46 |
| ▸ | EGFR | P00533 | 11/20 | 0.46 |
| ▸ | HCK | P08631 | 11/20 | 0.46 |
| ▸ | SRC | P12931 | 11/20 | 0.46 |
| ▸ | MTOR | P42345 | 11/20 | 0.46 |
| ▸ | EPHB4 | P54760 | 11/20 | 0.46 |
| ▸ | KDR | P35968 | 10/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 6/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.43 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.43 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129865 | 0.87 | PIK3CD (0.67) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19414298 | 0.86 | PIK3CD (0.44) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG | |
| SCHEMBL129486 | 0.74 | PIK3CD (0.73) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG | |
| SCHEMBL12551793 | 0.72 | PIK3CD (0.61) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG | |
| SCHEMBL130590 | 0.71 | SRC (0.73) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG | |
| SCHEMBL130589 | 0.71 | PIK3CG (0.74) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG | |
| SCHEMBL130421 | 0.71 | PIK3CD (0.78) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG | |
| SCHEMBL130612 | 0.70 | PIK3CD (0.65) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG | |
| SCHEMBL129820 | 0.70 | PIK3CD (0.76) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG | |
| SCHEMBL129870 | 0.69 | SRC (0.77) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10442783-B2 | 2,3-disubstituted chromen-4-one compounds as modulators of protein kinases | RHIZEN PHARMACEUTICALS SA (CH) | 2019-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10442783-B2 | 2,3-disubstituted chromen-4-one compounds as modulators of protein kinases | PIK3CB, PIK3CD, PDPK1 | PIK3CD 2/4885PRKDC 244/4885PIK3CA 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.