Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25162459 | 0.87 | DHODH (0.41) | DHODH | |
| SCHEMBL29251241 | 0.87 | DHODH (0.49) | DHODH | |
| SCHEMBL21469091 | 0.87 | DHODH (0.49) | DHODH | |
| SCHEMBL22940782 | 0.87 | DHODH (0.49) | DHODH | |
| SCHEMBL29251244 | 0.86 | DHODH (0.39) | DHODH | |
| SCHEMBL24075279 | 0.85 | DHODH (0.37) | DHODH | |
| SCHEMBL24074394 | 0.82 | DHODH (0.38) | DHODH | |
| SCHEMBL25162460 | 0.81 | DHODH (0.40) | DHODH | |
| SCHEMBL25162067 | 0.81 | DHODH (0.48) | DHODH | |
| SCHEMBL24074401 | 0.80 | DHODH (0.49) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236426-B | Process for preparing 2,4, 5-trisubstituted 1,2, 4-triazolones | 拜耳股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| US-20230257362-A1 | TRIAZOLONE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2023-08-17 | — | — | US | disclosed |
| WO-2023093812-A1 | CRYSTAL FORM OF TRIAZOLONE COMPOUND AND USE THEREOF | 南京明德新药研发有限公司 | 2023-06-01 | — | — | WO | disclosed |
| EP-4166551-A1 | TRIAZOLONE COMPOUND | Medshine Discovery Inc. (CN) | 2023-04-19 | — | — | EP | disclosed |
| US-11365179-B2 | Method for the preparation of a 2,4,5-trisubstituted 1,2,4-triazolone | BAYER AKTIENGESELLSCHAFT (DE) | 2022-06-21 | — | — | US | disclosed |
| WO-2021238881-A1 | TRIAZOLONE COMPOUND | 南京明德新药研发有限公司 | 2021-12-02 | — | — | WO | disclosed |
| US-20210032212-A1 | METHOD FOR THE PREPARATION OF A 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONE | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-04 | — | — | US | disclosed |
| CN-112236426-A | Process for preparing 2,4, 5-trisubstituted 1,2, 4-triazolones | 拜耳股份有限公司 | 2021-01-15 | — | — | CN | disclosed |
| WO-2019197239-A1 | METHOD FOR THE PREPARATION OF A 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONE | BAYER AKTIENGESELLSCHAFT (DE) | 2019-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257362-A1 | TRIAZOLONE COMPOUND | WNK3, SLC10A1, WNK2 | DHODH 3659/4885 |
| US-20210032212-A1 | METHOD FOR THE PREPARATION OF A 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONE | TES, CYP51A1, CYP4B1 | DHODH 1622/4885 |
| US-11365179-B2 | Method for the preparation of a 2,4,5-trisubstituted 1,2,4-triazolone | TES, CYP51A1, CYP4B1 | DHODH 1622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.