⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1178649 | 0.60 | — | — | |
| SCHEMBL17873075 | 0.58 | — | — | |
| SCHEMBL321091 | 0.57 | — | — | |
| SCHEMBL9098607 | 0.55 | — | — | |
| SCHEMBL2351542 | 0.53 | — | — | |
| SCHEMBL16534479 | 0.53 | — | — | |
| SCHEMBL25338556 | 0.52 | — | — | |
| SCHEMBL8749598 | 0.52 | — | — | |
| SCHEMBL25002994 | 0.50 | — | — | |
| SCHEMBL1703149 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729472-B1 | CARBOXYLIC ACID DERIVATIVES WITH AN OXAZOLO[4,5-C]PYRIDINE RING | SANOFI SA (FR) | 2016-08-24 | — | — | EP | disclosed |
| US-9321787-B2 | Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring | SANOFI (FR) | 2016-04-26 | — | — | US | disclosed |
| EP-2729473-B1 | CARBOXYLIC ACID DERIVATIVES WITH AN OXAZOLO[5,4-B]PYRIDINE RING | SANOFI SA (FR) | 2015-11-25 | — | — | EP | disclosed |
| EP-2729475-B1 | Carboxylic acid derivatives with an oxazolo[4,5-d]pyrimidine ring | SANOFI SA (FR) | 2015-06-10 | — | — | EP | disclosed |
| EP-2729471-B1 | CARBOXYLIC ACID DERIVATIVES WITH AN OXAZOLO[5,4-D]PYRIMIDINE RING | SANOFI SA (FR) | 2015-05-06 | — | — | EP | disclosed |
| US-8907093-B2 | Carboxylic acid derivatives having an oxazolo[4,5-c]pyridine ring | SANOFI (FR) | 2014-12-09 | — | — | US | disclosed |
| US-8846690-B2 | Heterocyclic carboxylic acid derivatives having a 2,5-substituted oxazolopyrimidine ring | SANOFI (FR) | 2014-09-30 | — | — | US | disclosed |
| US-8846692-B2 | Carboxylic acid derivatives having a 2,5-substituted oxazolopyrimidine ring | SANOFI (FR) | 2014-09-30 | — | — | US | disclosed |
| US-8846691-B2 | Heterocyclic carboxylic acid derivatives having a 2,5,7-substituted oxazolopyrimidine ring | SANOFI (FR) | 2014-09-30 | — | — | US | disclosed |
| US-8748436-B2 | Carboxylic acid derivatives having a 2,5,7-substituted oxazolopyrimidine ring | SANOFI (FR) | 2014-06-10 | — | — | US | disclosed |
| EP-2523959-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| EP-2523958-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| EP-2523960-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011086077-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |
| WO-2011086080-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |
| WO-2011086078-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |
| US-20030199560-A1 | Bisaryl compound and medicament for cancer treatment comprising the same | KYOWA HAKKO KOGYO CO., LTD. | 2003-10-23 | — | — | US | disclosed |
| US-6608061-B2 | Antiproliferative agents | KYOMA HAKKO KOGYO CO., LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| US-20030018070-A1 | BISARYL COMPOUND AND MEDICAMENT FOR CANCER TREATMENT COMPRISING THE SAME | FUJIFILM CORPORATION (JP) | 2003-01-23 | — | — | US | disclosed |
| EP-0990439-A1 | BISARYL COMPOUNDS AND CANCER REMEDIES CONTAINING THE SAME | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |