Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21462312 | 0.84 | MAOB (0.54) | MAOBADRA2AMAOAALOX5METAP2 | |
| SCHEMBL21472147 | 0.83 | MAOB (0.54) | MAOBADRA2AMAOAALOX5METAP2 | |
| SCHEMBL14934120 | 0.80 | MKNK1 (0.47) | MAOBADRA2AMAOAALOX5METAP2 | |
| SCHEMBL19180722 | 0.79 | MAOB (0.56) | MAOBADRA2AMAOAALOX5METAP2 | |
| SCHEMBL4661027 | 0.78 | MAOB (0.56) | MAOBADRA2AMAOAALOX5METAP2 | |
| SCHEMBL7826723 | 0.77 | MAOB (0.54) | MAOBADRA2AMAOAALOX5METAP2 | |
| SCHEMBL7125605 | 0.77 | MAOB (0.68) | MAOBADRA2AMAOAALOX5METAP2 | |
| SCHEMBL21462499 | 0.77 | MAOB (0.54) | MAOBADRA2AMAOAALOX5METAP2 | |
| SCHEMBL3687210 | 0.77 | MAOB (0.54) | MAOBADRA2AMAOAALOX5METAP2 | |
| SCHEMBL11673327 | 0.77 | MAOB (0.58) | MAOBADRA2AMAOAALOX5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019197502-A1 | SELECTIVE LIGANDS FOR TAU AGGREGATES | KARIN & STEN MORTSTEDT CBD SOLUTIONS AB (SE) | 2019-10-17 | — | — | WO | disclosed |