SCHEMBL21473563

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12534441	0.90	EGFR (0.85)	EGFRKDRFGFR1FLT1FLT4
	SCHEMBL2136770	0.89	EGFR (1.00)	EGFRKDRFGFR1FLT1FLT4
	Vandetanib SCHEMBL29352879	0.89	EGFR (1.00)	EGFRKDRFGFR1FLT1FLT4
	Vandetanib SCHEMBL9044	0.89	EGFR (1.00)	EGFRKDRFGFR1FLT1FLT4
	Vandetanib SCHEMBL28224661	0.89	EGFR (1.00)	EGFRKDRFGFR1FLT1FLT4
	SCHEMBL14095970	0.89	EGFR (1.00)	EGFRKDRFGFR1FLT1FLT4
	Vandetanib SCHEMBL1614458	0.89	EGFR (1.00)	EGFRKDRFGFR1FLT1FLT4
	SCHEMBL8173228	0.89	EGFR (0.82)	EGFRKDRFGFR1FLT1FLT4
	Vandetanib SCHEMBL4637084	0.89	EGFR (0.98)	EGFRKDRFGFR1FLT1FLT4
	SCHEMBL2137353	0.89	EGFR (0.98)	EGFRKDRFGFR1FLT1FLT4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.