Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 20/20 | 0.64 |
| ▸ | MAP3K6 | O95382 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21469775 | 0.91 | MAP3K5 (0.66) | MAP3K5MAP3K6 | |
| SCHEMBL21473790 | 0.85 | MAP3K5 (0.66) | MAP3K5 | |
| SCHEMBL21473915 | 0.82 | MAP3K5 (0.61) | MAP3K5 | |
| SCHEMBL21469856 | 0.81 | MAP3K5 (0.66) | MAP3K5 | |
| SCHEMBL14673153 | 0.78 | MAP3K5 (0.74) | MAP3K5MAP3K6 | |
| SCHEMBL21461142 | 0.78 | MAP3K5 (1.00) | MAP3K5 | |
| SCHEMBL31510415 | 0.78 | MAP3K5 (1.00) | MAP3K5 | |
| SCHEMBL21461023 | 0.78 | MAP3K5 (1.00) | MAP3K5 | |
| SCHEMBL31249048 | 0.78 | MAP3K5 (1.00) | MAP3K5 | |
| SCHEMBL21461025 | 0.77 | MAP3K5 (1.00) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019200267-A1 | TRICYCLIC ASK1 INHIBITORS | Terns, Inc. (US) | 2019-10-17 | — | — | WO | disclosed |