Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21473856 | 0.99 | CYP1B1 (0.33) | CYP1B1 | |
| SCHEMBL4088954 | 0.84 | KMT2A (0.35) | CYP1B1MEN1KMT2A | |
| SCHEMBL16216715 | 0.83 | CYP1B1 (0.34) | CYP1B1 | |
| SCHEMBL4083797 | 0.83 | KMT2A (0.34) | CYP1B1MEN1KMT2A | |
| SCHEMBL14133877 | 0.83 | KMT2A (0.35) | CYP1B1MEN1KMT2ATBK1 | |
| SCHEMBL16216712 | 0.82 | CYP1B1 (0.32) | CYP1B1 | |
| SCHEMBL23919457 | 0.81 | CYP2C19 (0.31) | CYP1B1MEN1KMT2A | |
| SCHEMBL23919455 | 0.79 | CYP1B1 (0.32) | CYP1B1 | |
| SCHEMBL18101629 | 0.79 | CYP1B1 (0.39) | CYP1B1MEN1KMT2A | |
| SCHEMBL23919453 | 0.79 | CYP1B1 (0.33) | CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11512039-B2 | Aromatic amine derivatives, preparation methods therefor, and uses thereof | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2022-11-29 | — | — | US | disclosed |
| US-20190315675-A1 | AROMATIC AMINE DERIVATIVES, PREPARATION METHODS THEREFOR, AND USES THEREOF | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315675-A1 | AROMATIC AMINE DERIVATIVES, PREPARATION METHODS THEREFOR, AND USES THEREOF | SLC7A1, WEE1, SLC7A5 | CYP1B1 326/4885MEN1 1863/4885KMT2A 2000/4885 |
| US-11512039-B2 | Aromatic amine derivatives, preparation methods therefor, and uses thereof | SLC7A1, WEE1, SLC7A5 | CYP1B1 326/4885MEN1 1863/4885KMT2A 2000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.