SCHEMBL21474076

SCHEMBL21474076

Brc1ccc2c(c1)CCc1c-2[nH]c2ccccc12

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.76
CA2 P00918 8/20 0.76
CA4 P22748 8/20 0.76
CA6 P23280 8/20 0.76
CCNB2 O95067 5/20 0.60
CDK1 P06493 5/20 0.60
CCNB1 P14635 5/20 0.60
CCNB3 Q8WWL7 5/20 0.60
GSK3B P49841 5/20 0.51
CDK5 Q00535 4/20 0.51
CDK5R1 Q15078 4/20 0.51
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
ALDH1A1 P00352 3/20 0.49
LMNA P02545 3/20 0.49
MAPT P10636 3/20 0.49
HSD17B10 Q99714 3/20 0.49
KDM4E B2RXH2 2/20 0.49
AURKA O14965 2/20 0.49
TSHR P16473 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30965989 0.89 CA1 (0.64) CA1CA2CA4CA6CCNB2
SCHEMBL21474134 0.88 CA1 (0.67) CA1CA2CA4CA6CCNB2
SCHEMBL12249832 0.84 CDK1 (0.84) CA1CA2CA4CA6CCNB2
SCHEMBL15451583 0.84 CDK1 (0.67) CA1CA2CA4CA6CCNB2
SCHEMBL12249830 0.82 CA1 (0.51) CA1CA2CA4CA6MEN1
SCHEMBL12126575 0.80 CA1 (0.71) CA1CA2CA4CA6CCNB2
SCHEMBL30063877 0.80 CA1 (0.71) CA1CA2CA4CA6CCNB2
SCHEMBL12301264 0.78 CA1 (0.78) CA1CA2CA4CA6MEN1
SCHEMBL16535396 0.78 CA1 (0.54) CA1CA2CA4CA6CCNB2
SCHEMBL30966014 0.77 CA1 (0.57) CA1CA2CA4CA6CCNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019198934-A1 COMPOSITION, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE 삼성에스디아이 주식회사 2019-10-17 WO disclosed
EP-3553050-A1 COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE Samsung SDI Co., Ltd. (KR) 2019-10-16 EP disclosed