Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TAS2R46 | P59540 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23008236 | 1.00 | ICAM1 (0.41) | ICAM1CYP3A4RECQLTDP1CYP1A2 | |
| SCHEMBL21475294 | 1.00 | ICAM1 (0.41) | ICAM1CYP3A4RECQLTDP1CYP1A2 | |
| SCHEMBL21475311 | 0.88 | ICAM1 (0.39) | ICAM1CYP3A4RECQLTDP1CYP1A2 | |
| SCHEMBL21475324 | 0.88 | ICAM1 (0.39) | ICAM1CYP3A4RECQLTDP1CYP1A2 | |
| SCHEMBL23007750 | 0.88 | ICAM1 (0.39) | ICAM1CYP3A4RECQLTDP1CYP1A2 | |
| SCHEMBL23007847 | 0.85 | ICAM1 (0.38) | ICAM1CYP3A4RECQLTDP1CYP1A2 | |
| SCHEMBL23007849 | 0.85 | ICAM1 (0.38) | ICAM1CYP3A4RECQLTDP1CYP1A2 | |
| SCHEMBL23007846 | 0.85 | ICAM1 (0.38) | ICAM1CYP3A4RECQLTDP1CYP1A2 | |
| SCHEMBL23007818 | 0.85 | ICAM1 (0.38) | ICAM1CYP3A4RECQLTDP1CYP1A2 | |
| SCHEMBL23007816 | 0.85 | ICAM1 (0.38) | ICAM1CYP3A4RECQLTDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019198678-A1 | NOVEL LACTONE COMPOUND AND NOVEL ETHER COMPOUND | 高砂香料工業株式会社 | 2019-10-17 | — | — | WO | disclosed |