Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 20/20 | 0.75 |
| ▸ | HDAC1 | Q13547 | 19/20 | 0.75 |
| ▸ | HDAC3 | O15379 | 17/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13736541 | 0.86 | HDAC1 (1.00) | HDAC2HDAC1HDAC3 | |
| SCHEMBL13735344 | 0.76 | HDAC2 (0.67) | HDAC2HDAC1HDAC3 | |
| SCHEMBL13738266 | 0.71 | HDAC1 (1.00) | HDAC2HDAC1HDAC3 | |
| SCHEMBL21476944 | 0.71 | HDAC1 (0.55) | HDAC2HDAC1HDAC3 | |
| SCHEMBL4580520 | 0.69 | HDAC3 (0.58) | HDAC2HDAC1HDAC3 | |
| SCHEMBL15624636 | 0.69 | HDAC2 (0.58) | HDAC2HDAC1HDAC3 | |
| SCHEMBL13735639 | 0.69 | HDAC2 (1.00) | HDAC2HDAC1HDAC3 | |
| SCHEMBL13833475 | 0.69 | HDAC2 (1.00) | HDAC2HDAC1HDAC3 | |
| SCHEMBL4579506 | 0.69 | HDAC2 (0.57) | HDAC2HDAC1HDAC3 | |
| SCHEMBL4580675 | 0.68 | HDAC1 (0.58) | HDAC2HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2701699-B1 | INHIBITORS OF HISTONE DEACETYLASE | BROAD INST INC (US) | 2019-10-16 | — | — | EP | disclosed |