Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TACR2 | P21452 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22560634 | 0.83 | HRH3 (0.40) | HRH3KDM4EALDH1A1TDP1MAPT | |
| SCHEMBL3051997 | 0.79 | HRH3 (0.43) | HRH3KDM4EALDH1A1TDP1 | |
| SCHEMBL20148585 | 0.70 | HRH3 (0.55) | HRH3KDM4EALDH1A1TDP1 | |
| SCHEMBL18705095 | 0.70 | HRH3 (0.52) | HRH3KDM4EALDH1A1 | |
| SCHEMBL20324223 | 0.69 | HRH4 (0.44) | HRH3KDM4EALDH1A1TDP1MAPT | |
| SCHEMBL25109032 | 0.69 | KDM4E (0.49) | HRH3KDM4EALDH1A1TDP1 | |
| SCHEMBL3068170 | 0.69 | HRH3 (0.57) | HRH3KDM4EALDH1A1TDP1 | |
| SCHEMBL18705087 | 0.69 | HRH3 (0.54) | HRH3KDM4EALDH1A1TDP1 | |
| SCHEMBL20148588 | 0.69 | HRH3 (0.54) | HRH3KDM4EALDH1A1TDP1 | |
| SCHEMBL18705081 | 0.68 | DDB1 (0.48) | HRH3KDM4EALDH1A1TDP1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199816-A1 | CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME | ARVINAS OPERATIONS, INC. (US) | 2019-10-17 | — | — | WO | disclosed |