Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 4/20 | 0.49 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | DGKA | P23743 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25670236 | 1.00 | CYP3A4 (0.56) | CYP3A4TSHRATMTDP1LMNA | |
| SCHEMBL18202072 | 1.00 | CYP3A4 (0.56) | CYP3A4TSHRATMTDP1LMNA | |
| SCHEMBL25670246 | 1.00 | CYP3A4 (0.56) | CYP3A4TSHRATMTDP1LMNA | |
| SCHEMBL26356022 | 1.00 | CYP3A4 (0.56) | CYP3A4TSHRATMTDP1LMNA | |
| SCHEMBL18202089 | 1.00 | CYP3A4 (0.56) | CYP3A4TSHRATMTDP1LMNA | |
| SCHEMBL18804786 | 1.00 | CYP3A4 (0.56) | CYP3A4TSHRATMTDP1LMNA | |
| SCHEMBL24314127 | 1.00 | CYP3A4 (0.56) | CYP3A4TSHRATMTDP1LMNA | |
| SCHEMBL21478864 | 1.00 | CYP3A4 (0.56) | CYP3A4TSHRATMTDP1LMNA | |
| SCHEMBL20627951 | 1.00 | CYP3A4 (0.56) | CYP3A4TSHRATMTDP1LMNA | |
| SCHEMBL18804800 | 1.00 | CYP3A4 (0.56) | CYP3A4TSHRATMTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190314524-A1 | NOVEL LIPIDS AND LIPID NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACIDS | ACUITAS THERAPEUTICS INC (CA) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190314524-A1 | NOVEL LIPIDS AND LIPID NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACIDS | PHOSPHO1, LPAR1, NPC1 | CYP3A4 3989/4885TSHR 1707/4885ATM 3554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.