Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SF3B3 | Q15393 | 8/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23404451 | 1.00 | SF3B3 (0.42) | SF3B3BRD4CREBBP | |
| SCHEMBL31713952 | 1.00 | SF3B3 (0.42) | SF3B3BRD4CREBBP | |
| SCHEMBL21482589 | 1.00 | SF3B3 (0.42) | SF3B3BRD4CREBBP | |
| SCHEMBL23404455 | 1.00 | SF3B3 (0.42) | SF3B3BRD4CREBBP | |
| SCHEMBL31208473 | 1.00 | SF3B3 (0.42) | SF3B3BRD4CREBBP | |
| SCHEMBL31713982 | 0.92 | SF3B3 (0.41) | SF3B3 | |
| SCHEMBL31714019 | 0.92 | SF3B3 (0.41) | SF3B3 | |
| SCHEMBL21482590 | 0.90 | SF3B3 (0.44) | SF3B3BRD4CREBBP | |
| SCHEMBL21482637 | 0.90 | SF3B3 (0.44) | SF3B3BRD4CREBBP | |
| SCHEMBL23404543 | 0.90 | SF3B3 (0.44) | SF3B3BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199667-A2 | CERTAIN PLADIENOLIDE COMPOUNDS AND METHODS OF USE | KEANEY GREGG F (US) | 2019-10-17 | — | — | WO | disclosed |