Phytosphingosine

Phytosphingosine

SCHEMBL21484046

CCCCCCCCCCCCCCC(O)C(O)C(N)CO.CCCCCCCCCCCCCCC(O)C(O)C(N)CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 4/20 0.78
SPHK1 Q9NYA1 4/20 0.78
LMNA P02545 4/20 0.78
MAPT P10636 4/20 0.78
GMNN O75496 3/20 0.78
POLB P06746 3/20 0.78
BLM P54132 3/20 0.78
CETP P11597 3/20 0.78
UBE2N P61088 3/20 0.78
THPO P40225 2/20 0.78
TP53 P04637 2/20 0.78
CYP1A2 P05177 2/20 0.78
MTOR P42345 1/20 0.78
KDM4E B2RXH2 1/20 0.78
CYP3A4 P08684 1/20 0.78
HTT P42858 1/20 0.78
CSNK1E P49674 1/20 0.47
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
GLA P06280 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7171764 1.00 CYP2D6 (0.78) CYP2D6SPHK1LMNAMAPTGMNN
SCHEMBL13780782 1.00 CYP2D6 (0.78) CYP2D6SPHK1LMNAMAPTGMNN
Phytosphingosine SCHEMBL5490039 1.00 CYP2D6 (0.78) CYP2D6SPHK1LMNAMAPTGMNN
Phytosphingosine SCHEMBL13146498 1.00 CYP2D6 (0.78) CYP2D6SPHK1LMNAMAPTGMNN
SCHEMBL12279953 1.00 CYP2D6 (0.78) CYP2D6SPHK1LMNAMAPTGMNN
Phytosphingosine SCHEMBL12563454 1.00 CYP2D6 (0.78) CYP2D6SPHK1LMNAMAPTGMNN
Phytosphingosine SCHEMBL14415162 1.00 CYP2D6 (0.78) CYP2D6SPHK1LMNAMAPTGMNN
Phytosphingosine SCHEMBL833646 1.00 CYP2D6 (0.78) CYP2D6SPHK1LMNAMAPTGMNN
Phytosphingosine SCHEMBL14565602 1.00 CYP2D6 (0.78) CYP2D6SPHK1LMNAMAPTGMNN
SCHEMBL29822750 1.00 CYP2D6 (0.78) CYP2D6SPHK1LMNAMAPTGMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3554310-A1 PACKAGED SKIN TREATMENT COMPOSITION AND METHOD ELC Management LLC (US) 2019-10-23 EP disclosed
CN-108473968-A The method for producing phytosphingosine or dihydrosphingosine 味之素株式会社 2018-08-31 CN disclosed
CN-107374992-A The crease-resistant Face-protecting mask that compacts of lycopene 吕玲 2017-11-24 CN disclosed
CN-101434558-A Salicylic acid-sphingoid base derivative and uses thereof COSMOFUMU CORP (NL) 2009-05-20 CN disclosed