Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154323 | 0.99 | AURKA (0.72) | AURKAAURKB | |
| SCHEMBL2146470 | 0.94 | AURKA (0.72) | AURKAAURKB | |
| SCHEMBL2159881 | 0.94 | AURKA (0.72) | AURKAAURKB | |
| SCHEMBL2200158 | 0.93 | AURKA (0.64) | AURKAAURKB | |
| SCHEMBL2146245 | 0.92 | AURKA (0.68) | AURKAAURKB | |
| SCHEMBL2161126 | 0.92 | AURKA (0.68) | AURKAAURKB | |
| SCHEMBL2146345 | 0.92 | AURKA (0.68) | AURKAAURKB | |
| SCHEMBL2146579 | 0.92 | AURKA (0.68) | AURKAAURKB | |
| SCHEMBL2148775 | 0.92 | AURKA (0.61) | AURKAAURKB | |
| SCHEMBL2146093 | 0.91 | AURKA (0.69) | AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088045-A1 | AURORA KINASE COMPOUNDS AND METHODS OF THEIR USE | AMBIT BIOSCIENCES CORPORATION (US) | 2011-07-21 | — | — | WO | claimed |
| WO-2011088045-A1 | AURORA KINASE COMPOUNDS AND METHODS OF THEIR USE | AMBIT BIOSCIENCES CORPORATION (US) | 2011-07-21 | — | — | WO | disclosed |