⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532335 | 0.74 | — | — | |
| SCHEMBL15440778 | 0.74 | — | — | |
| SCHEMBL27701870 | 0.72 | — | — | |
| SCHEMBL9623477 | 0.72 | — | — | |
| SCHEMBL11047737 | 0.69 | — | — | |
| SCHEMBL1173981 | 0.68 | — | — | |
| SCHEMBL21891510 | 0.67 | — | — | |
| SCHEMBL29064146 | 0.64 | — | — | |
| SCHEMBL11134128 | 0.62 | — | — | |
| SCHEMBL6915285 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2702045-B1 | NOVEL PROCESS FOR THE PREPARATION OF ETRAVIRINE | MYLAN LABORATORIES LTD (IN) | 2017-10-18 | — | — | EP | disclosed |
| EP-2342186-B1 | PROCESS FOR SYNTHESIS OF ETRAVIRINE | EMCURE PHARMACEUTICALS LTD (IN) | 2014-09-17 | — | — | EP | disclosed |
| EP-2702045-A1 | NOVEL PROCESS FOR THE PREPARATION OF ETRAVIRINE | Mylan Laboratories, Limited (IN) | 2014-03-05 | — | — | EP | disclosed |
| US-8653266-B2 | Process for the production of etravirine | MYLAN LABORATORIES LIMITED (IN) | 2014-02-18 | — | — | US | disclosed |
| US-20130116433-A1 | PROCESS FOR THE PRODUCTION OF ETRAVIRINE | MYLAN LABORATORIES LIMITED (IN) | 2013-05-09 | — | — | US | disclosed |
| WO-2012147104-A1 | NOVEL PROCESS FOR THE PREPARATION OF ETRAVIRINE | MYLAN LABORATORIES LTD (IN) | 2012-11-01 | — | — | WO | disclosed |
| US-20110196156-A1 | PROCESS FOR SYNTHESIS OF DIARYLPYRIMIDINE NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR | GURJAR MUKUND KESHAV | 2011-08-11 | — | — | US | disclosed |
| EP-2342186-A2 | PROCESS FOR SYNTHESIS OF DIARYLPYRIMIDINE NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR | Emcure Pharmaceuticals Limited (IN) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010150279-A2 | PROCESS FOR SYNTHESIS OF DIARYLPYRIMIDINE NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR | EMCURE PHARMACEUTICALS LIMITED (IN) | 2010-12-29 | — | — | WO | disclosed |