Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19701366 | 1.00 | SMYD3 (0.51) | SMYD3HSD11B1 | |
| SCHEMBL19701368 | 0.84 | SMYD3 (0.50) | SMYD3HSD11B1 | |
| SCHEMBL21489946 | 0.84 | SMYD3 (0.50) | SMYD3HSD11B1 | |
| SCHEMBL29793588 | 0.84 | CNR2 (0.59) | HSD11B1 | |
| SCHEMBL21490222 | 0.83 | SMYD3 (0.67) | SMYD3 | |
| SCHEMBL19710069 | 0.83 | SMYD3 (0.67) | SMYD3 | |
| SCHEMBL21490050 | 0.81 | SMYD3 (0.50) | SMYD3HSD11B1 | |
| SCHEMBL19701358 | 0.81 | SMYD3 (0.50) | SMYD3HSD11B1 | |
| SCHEMBL24296470 | 0.79 | CNR2 (0.53) | SMYD3HSD11B1 | |
| SCHEMBL19691131 | 0.78 | SMYD3 (0.71) | SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210198252-A1 | SMYD INHIBITORS | EPIZYME INC (US) | 2021-07-01 | — | — | US | claimed |
| US-20190322660-A1 | SMYD INHIBITORS | Epizyme, Inc. | 2019-10-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198252-A1 | SMYD INHIBITORS | SMYD3, SMYD2, SMURF2 | SMYD3 1/4885HSD11B1 4033/4885 |
| US-20190322660-A1 | SMYD INHIBITORS | SMYD2, SMYD3, SMURF2 | SMYD3 2/4885HSD11B1 3729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.