Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 11/20 | 0.69 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.53 |
| ▸ | ATXN2 | Q99700 | 3/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17591753 | 1.00 | SMYD3 (0.69) | SMYD3ENPP2ATXN2KCNH2 | |
| SCHEMBL17591754 | 1.00 | SMYD3 (0.69) | SMYD3ENPP2ATXN2KCNH2 | |
| SCHEMBL23575871 | 0.82 | SMYD3 (1.00) | SMYD3 | |
| SCHEMBL17591802 | 0.82 | SMYD3 (1.00) | SMYD3 | |
| SCHEMBL17591810 | 0.82 | SMYD3 (1.00) | SMYD3 | |
| Hydrochloric Acid SCHEMBL20906683 | 0.82 | SMYD3 (0.98) | SMYD3 | |
| Hydrochloric Acid SCHEMBL17591890 | 0.82 | SMYD3 (0.98) | SMYD3 | |
| Hydrochloric Acid SCHEMBL20906682 | 0.82 | SMYD3 (0.98) | SMYD3 | |
| Hydrochloric Acid SCHEMBL17591889 | 0.82 | SMYD3 (0.98) | SMYD3 | |
| Hydrochloric Acid SCHEMBL17591887 | 0.82 | SMYD3 (0.98) | SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190322660-A1 | SMYD INHIBITORS | Epizyme, Inc. | 2019-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190322660-A1 | SMYD INHIBITORS | SMYD2, SMYD3, SMURF2 | SMYD3 2/4885ENPP2 2026/4885ATXN2 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.