Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.54 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.54 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 4/20 | 0.56 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.54 |
| ▸ | INSR | P06213 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL554666 | 1.00 | KDM4A (0.56) | KDM4AKDM2AALDH1A1MEN1LMNA | |
| Iodide SCHEMBL28531710 | 1.00 | KDM4A (0.56) | KDM4AKDM2AALDH1A1MEN1LMNA | |
| Iodide SCHEMBL187218 | 1.00 | KDM4A (0.56) | KDM4AKDM2AALDH1A1MEN1LMNA | |
| Iodide SCHEMBL592580 | 1.00 | KDM4A (0.56) | KDM4AKDM2AALDH1A1MEN1LMNA | |
| Iodide SCHEMBL554665 | 1.00 | KDM4A (0.56) | KDM4AKDM2AALDH1A1MEN1LMNA | |
| Iodide SCHEMBL3954408 | 1.00 | KDM4A (0.56) | KDM4AKDM2AALDH1A1MEN1LMNA | |
| Iodide SCHEMBL3954410 | 1.00 | KDM4A (0.56) | KDM4AKDM2AALDH1A1MEN1LMNA | |
| Iodide SCHEMBL28531712 | 1.00 | KDM4A (0.56) | KDM4AKDM2AALDH1A1MEN1LMNA | |
| Iodide SCHEMBL187217 | 1.00 | KDM4A (0.56) | KDM4AKDM2AALDH1A1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL4634452 | 0.99 | KDM4A (0.55) | KDM4AKDM2AALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11150358-B2 | Radiation dosimetry sol or gel and radiation dosimeter comprising same as material for radiation dosimetry | RIKEN (JP) | 2021-10-19 | — | — | US | disclosed |
| US-20200333474-A1 | RADIATION DOSIMETRY SOL OR GEL AND RADIATION DOSIMETER COMPRISING SAME AS MATERIAL FOR RADIATION DOSIMETRY | RIKEN (JP) | 2020-10-22 | — | — | US | disclosed |
| EP-3686632-A1 | RADIATION DOSIMETRY SOL OR GEL AND RADIATION DOSIMETER COMPRISING SAME AS MATERIAL FOR RADIATION DOSIMETRY | Riken (JP) | 2020-07-29 | — | — | EP | disclosed |
| WO-2019201221-A1 | MODIFIED STARCH AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 瑞辰星生物技术（广州）有限公司 | 2019-10-24 | — | — | WO | disclosed |