SCHEMBL2149661

SCHEMBL2149661

CCCCC1(OP(=O)(O)OC2(CCCC)CCCCC2)CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 4/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
LPAR3 Q9UBY5 6/20 0.32
LPAR2 Q9HBW0 3/20 0.32
LPAR1 Q92633 2/20 0.32
CETP P11597 2/20 0.32
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31
S1PR1 P21453 2/20 0.31
S1PR3 Q99500 2/20 0.31
S1PR5 Q9H228 2/20 0.31
FDPS P14324 1/20 0.31
S1PR4 O95977 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2149687 0.95 SMPD1 (0.34) SMPD1MEN1KMT2ALPAR3LPAR2
SCHEMBL2150185 0.89 SMPD1 (0.37) SMPD1MEN1KMT2ALPAR3LPAR2
SCHEMBL2149789 0.87 TSHR (0.30) TSHRCYP2C19
SCHEMBL28395278 0.86 SMN1; SMN2 (0.32) SMPD1MEN1KMT2ALPAR3LPAR2
SCHEMBL2150182 0.85 CYP3A4 (0.34) MEN1KMT2ACETPTSHR
SCHEMBL28389060 0.84 SMPD1 (0.33) SMPD1MEN1KMT2ALPAR3LPAR2
SCHEMBL2150533 0.84 SMPD1 (0.38) SMPD1LPAR3LPAR2LPAR1S1PR1
SCHEMBL11030099 0.83 SMPD1 (0.42) SMPD1LPAR3LPAR2LPAR1S1PR1
SCHEMBL2149658 0.81 TSHR (0.35) TSHRCYP2C19
SCHEMBL2150530 0.79 CYP3A4 (0.35) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2341091-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND METHOD FOR PREPARING THE OPTICAL MATERIAL MITSUI CHEMICALS INC (JP) 2013-12-04 EP disclosed
US-8434866-B2 Polymerizable composition for optical material, optical material, and method for preparing the optical material MITSUI CHEMICALS, INC. (JP) 2013-05-07 US disclosed
EP-2341091-A1 POLYMERIZABLE COMPOUND FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND OPTICAL MATERIAL MANUFACTURING METHOD Mitsui Chemicals, Inc. (JP) 2011-07-06 EP disclosed
US-20100075154-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND METHOD FOR PREPARING THE OPTICAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2010-03-25 US disclosed