Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 20/20 | 0.75 |
| ▸ | CCND3 | P30281 | 20/20 | 0.75 |
| ▸ | CDK6 | Q00534 | 17/20 | 0.75 |
| ▸ | CDK1 | P06493 | 14/20 | 0.75 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.62 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.62 |
| ▸ | CDK2 | P24941 | 2/20 | 0.62 |
| ▸ | CDK7 | P50613 | 2/20 | 0.62 |
| ▸ | CDK9 | P50750 | 2/20 | 0.62 |
| ▸ | CCNH | P51946 | 2/20 | 0.62 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18191700 | 0.88 | CDK4 (0.73) | CDK4CCND3CDK6CDK1CCNT1 | |
| SCHEMBL20528183 | 0.88 | CDK4 (0.79) | CDK4CCND3CDK6CDK1CCNT1 | |
| SCHEMBL18191681 | 0.88 | CDK4 (0.79) | CDK4CCND3CDK6CDK1CCNT1 | |
| SCHEMBL18191712 | 0.88 | CDK4 (0.73) | CDK4CCND3CDK6CDK1CCNT1 | |
| SCHEMBL18191752 | 0.88 | CDK4 (0.86) | CDK4CCND3CDK6CDK1CDK2 | |
| SCHEMBL29686798 | 0.88 | CDK4 (0.70) | CDK4CCND3CDK6CDK1CCNT1 | |
| SCHEMBL18191753 | 0.88 | CDK4 (0.70) | CDK4CCND3CDK6CDK1CCNT1 | |
| SCHEMBL21499040 | 0.87 | CDK4 (0.65) | CDK4CCND3CDK6CDK1CCNT1 | |
| SCHEMBL20528275 | 0.87 | CDK4 (0.65) | CDK4CCND3CDK6CDK1CCNT1 | |
| SCHEMBL18191696 | 0.87 | CDK4 (0.65) | CDK4CCND3CDK6CDK1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450316-B2 | Certain protein kinase inhibitor | Chongqing Fochon Pharmaceutical Co., Ltd. (CN) | 2019-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450316-B2 | Certain protein kinase inhibitor | CDK4, CDK6, CDK2 | CDK4 1/4885CCND3 96/4885CDK6 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.