SCHEMBL21500126

SCHEMBL21500126

COc1ccccc1CCC(=O)N(Cc1ccncc1)Cc1cccc(OCCc2ccc(F)cc2)c1

nearest known ligand 0.72

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 14/20 0.72
SLC2A4 P14672 3/20 0.72
SLC2A8 Q9NY64 1/20 0.68
ABCB1 P08183 1/20 0.45
TSHR P16473 2/20 0.45
USP2 O75604 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20338615 0.84 SLC2A1 (1.00) SLC2A1SLC2A4SLC2A8TSHRUSP2
SCHEMBL21500123 0.81 SLC2A4 (1.00) SLC2A1SLC2A4SLC2A8
SCHEMBL23269336 0.77 SLC2A1 (0.74) SLC2A1SLC2A4SLC2A8
SCHEMBL20339794 0.77 SLC2A1 (0.71) SLC2A1SLC2A4SLC2A8TSHR
SCHEMBL20339979 0.76 SLC2A1 (1.00) SLC2A1SLC2A4SLC2A8
SCHEMBL20339753 0.76 SLC2A1 (1.00) SLC2A1SLC2A4SLC2A8
SCHEMBL20339799 0.73 SLC2A1 (1.00) SLC2A1SLC2A4SLC2A8
SCHEMBL20339353 0.73 SLC2A1 (1.00) SLC2A1SLC2A4SLC2A8
SCHEMBL20339757 0.72 SLC2A1 (1.00) SLC2A1SLC2A4SLC2A8
SCHEMBL25722411 0.70 SLC2A1 (0.62) SLC2A1SLC2A4SLC2A8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190321345-A1 GLUT4 Selective Inhibitors for Cancer Therapy UNIV EMORY (US) 2019-10-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190321345-A1 GLUT4 Selective Inhibitors for Cancer Therapy SLC2A4, SLC2A1, SLC2A2 SLC2A1 2/4885SLC2A4 1/4885SLC2A8 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.