Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.70 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.70 |
| ▸ | PSMB5 | P28074 | 8/20 | 0.40 |
| ▸ | PSMB2 | P49721 | 6/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | TERF2IP | Q9NYB0 | 6/20 | 0.38 |
| ▸ | TERF2 | Q15554 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21473990 | 0.90 | KDM1A (0.86) | KDM1ARCOR1PSMB5PSMB2SLC40A1 | |
| SCHEMBL21473992 | 0.90 | KDM1A (0.85) | KDM1ARCOR1PSMB5PSMB2SLC40A1 | |
| SCHEMBL21474047 | 0.90 | KDM1A (0.85) | KDM1ARCOR1PSMB5PSMB2SLC40A1 | |
| SCHEMBL25639947 | 0.89 | KDM1A (0.70) | KDM1ARCOR1PSMB5PSMB2SLC40A1 | |
| SCHEMBL21473991 | 0.89 | KDM1A (0.85) | KDM1ARCOR1PSMB5PSMB2SLC40A1 | |
| SCHEMBL21504353 | 0.89 | KDM1A (0.85) | KDM1ARCOR1PSMB5PSMB2SLC40A1 | |
| Polymyxin B3 SCHEMBL21474115 | 0.86 | KDM1A (0.91) | KDM1ARCOR1PSMB5PSMB2SLC40A1 | |
| Polymyxin B5 SCHEMBL21258460 | 0.86 | KDM1A (0.91) | KDM1ARCOR1PSMB5PSMB2SLC40A1 | |
| Polymyxin B4 SCHEMBL21476967 | 0.86 | KDM1A (0.91) | KDM1ARCOR1PSMB5PSMB2SLC40A1 | |
| SCHEMBL21474044 | 0.86 | KDM1A (0.85) | KDM1ARCOR1TERF2IPTERF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3556769-A1 | POLYMYXIN DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) | 2019-10-23 | — | — | EP | disclosed |