Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.95 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.95 |
| ▸ | SSTR5 | P35346 | 8/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 7/20 | 0.42 |
| ▸ | SSTR2 | P30874 | 6/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | LDHB | P07195 | 1/20 | 0.41 |
| ▸ | TERF2IP | Q9NYB0 | 2/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21504123 | 1.00 | KDM1A (0.95) | KDM1ARCOR1SSTR5SSTR4SSTR2 | |
| SCHEMBL21474137 | 0.98 | KDM1A (0.91) | KDM1ARCOR1SSTR5SSTR4SSTR2 | |
| SCHEMBL21504117 | 0.98 | KDM1A (0.91) | KDM1ARCOR1SSTR5SSTR4SSTR2 | |
| Polymyxin B2 SCHEMBL534885 | 0.98 | KDM1A (1.00) | KDM1ARCOR1SSTR5SSTR4SSTR2 | |
| Polymyxin B2 SCHEMBL15887064 | 0.98 | KDM1A (1.00) | KDM1ARCOR1SSTR5SSTR4SSTR2 | |
| SCHEMBL21504327 | 0.95 | KDM1A (0.94) | KDM1ARCOR1SSTR5SSTR4SSTR2 | |
| SCHEMBL21474069 | 0.95 | KDM1A (0.94) | KDM1ARCOR1SSTR5SSTR4SSTR2 | |
| SCHEMBL21474062 | 0.94 | KDM1A (0.85) | KDM1ARCOR1PSMB5PSMB2 | |
| SCHEMBL21504378 | 0.94 | KDM1A (0.85) | KDM1ARCOR1PSMB5PSMB2 | |
| SCHEMBL21474061 | 0.94 | KDM1A (0.85) | KDM1ARCOR1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3556769-B1 | POLYMYXIN DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | INST MED BIOTECHNOLOGY CAMS (CN) | 2023-06-14 | — | — | EP | disclosed |
| EP-3556769-A1 | POLYMYXIN DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) | 2019-10-23 | — | — | EP | disclosed |