Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 8/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14979998 | 0.84 | GRM7 (0.41) | GRM7MTNR1AMTNR1BMAPTGAA | |
| SCHEMBL239019 | 0.83 | GRM7 (0.40) | GRM7OPRM1OPRD1OPRK1PYGL | |
| SCHEMBL27923521 | 0.83 | GRM7 (0.40) | GRM7OPRM1OPRD1OPRK1PYGL | |
| SCHEMBL14025206 | 0.82 | GRM7 (0.41) | GRM7MTNR1AMTNR1BMAPTGAA | |
| SCHEMBL805196 | 0.82 | GRM7 (0.44) | GRM7OPRM1OPRD1OPRK1MTNR1A | |
| SCHEMBL12966499 | 0.82 | GRM7 (0.44) | GRM7OPRM1OPRD1OPRK1MTNR1A | |
| SCHEMBL29911641 | 0.80 | EPHX2 (0.44) | EPHX2 | |
| SCHEMBL5389519 | 0.80 | EPHX2 (0.44) | EPHX2 | |
| SCHEMBL1598690 | 0.80 | EPHX2 (0.44) | EPHX2 | |
| SCHEMBL4816579 | 0.80 | EPHX2 (0.44) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780026-B1 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME (US) | 2019-10-23 | — | — | EP | disclosed |