Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 19/20 | 0.48 |
| ▸ | PRKDC | P78527 | 3/20 | 0.48 |
| ▸ | MTOR | P42345 | 11/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.39 |
| ▸ | ATR | Q13535 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29969316 | 1.00 | ATM (0.48) | ATMPRKDCMTORPIK3CAATR | |
| SCHEMBL29968565 | 0.83 | ATM (0.54) | ATMPRKDCMTORPIK3CAATR | |
| SCHEMBL29968617 | 0.82 | ATM (0.53) | ATMPRKDCMTORPIK3CAATR | |
| Hydrochloric Acid SCHEMBL26130925 | 0.82 | PRKDC (0.61) | ATMPRKDCMTORPIK3CAATR | |
| SCHEMBL29969341 | 0.81 | ATM (0.52) | ATMPRKDCMTORPIK3CAATR | |
| SCHEMBL29969038 | 0.80 | ATM (0.47) | ATMPRKDCMTORPIK3CAATR | |
| SCHEMBL21851110 | 0.79 | ATM (0.63) | ATMPRKDCMTORPIK3CAATR | |
| SCHEMBL29968726 | 0.79 | ATM (0.53) | ATMPRKDCMTORPIK3CAATR | |
| SCHEMBL24089043 | 0.79 | ATM (0.47) | ATMPRKDCMTORPIK3CAATR | |
| SCHEMBL21851103 | 0.78 | ATM (0.58) | ATMPRKDCMTORPIK3CAATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019201283-A1 | DUAL ATM AND DNA-PK INHIBITORS FOR USE IN ANTI-TUMOR THERAPY | XRAD THERAPEUTICS, INC. (US) | 2019-10-24 | — | — | WO | disclosed |