Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 18/20 | 0.48 |
| ▸ | JAK2 | O60674 | 7/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21514005 | 1.00 | NTRK1 (0.48) | NTRK1JAK2PIK3CGNTRK3 | |
| SCHEMBL21494188 | 0.89 | NTRK1 (0.48) | NTRK1JAK2PIK3CGNTRK3 | |
| SCHEMBL21494234 | 0.89 | NTRK1 (0.48) | NTRK1JAK2PIK3CGNTRK3 | |
| SCHEMBL23000159 | 0.89 | NTRK1 (0.48) | NTRK1JAK2PIK3CGNTRK3 | |
| SCHEMBL29746839 | 0.83 | NTRK1 (0.47) | NTRK1JAK2PIK3CGNTRK3 | |
| SCHEMBL23000184 | 0.78 | NTRK1 (0.47) | NTRK1JAK2 | |
| SCHEMBL21494184 | 0.78 | NTRK1 (0.47) | NTRK1JAK2 | |
| SCHEMBL21513608 | 0.78 | NTRK1 (0.47) | NTRK1JAK2NTRK3 | |
| SCHEMBL12495104 | 0.76 | NTRK1 (0.57) | NTRK1JAK2NTRK3 | |
| SCHEMBL12526210 | 0.75 | NTRK1 (0.57) | NTRK1JAK2NTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019201282-A1 | MACROCYCLIC KINASE INHIBITOR | 成都先导药物开发股份有限公司 | 2019-10-24 | — | — | WO | disclosed |