SCHEMBL215141

SCHEMBL215141

N[C@@H](Cc1ccccc1)C(=O)OC=O

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.59
ALPI P09923 1/20 0.59
PKM P14618 1/20 0.59
PTGS1 P23219 1/20 0.59
XIAP P98170 1/20 0.59
LTA4H P09960 1/20 0.53
SLC15A1 P46059 3/20 0.51
SLC1A3 P43003 2/20 0.47
SLC1A2 P43004 2/20 0.47
SLC1A1 P43005 2/20 0.47
HDAC8 Q9BY41 2/20 0.46
SRR Q9GZT4 2/20 0.46
CTSC P53634 1/20 0.44
CYP1A2 P05177 1/20 0.44
EPHX1 P07099 1/20 0.44
ANPEP P15144 1/20 0.43
LAP3 P28838 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4421753 1.00 SLC7A5 (0.59) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL15323730 0.90 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL6521570 0.85 SLC7A5 (0.59) SLC7A5HDAC8
SCHEMBL20873690 0.85 ALPI (0.58) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL6593251 0.85 ALPI (0.58) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL6586336 0.85 ALPI (0.58) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL28148514 0.85 SLC7A5 (0.59) SLC7A5HDAC8
SCHEMBL2785098 0.83 SLC7A5 (0.70) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL28291992 0.82 SLC7A5 (0.63) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL288607 0.82 SLC7A5 (0.68) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 337 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6617127-B2 Using N-formylaspartylphenylalanine compound HOLLAND SWEETENER COMPANY, V.O.F. (NL) 2003-09-09 US claimed
EP-1140982-B1 SYNTHESIS AND RECOVERY OF ASPARTAME INVOLVING ENZYMATIC DEFORMYLATION STEP HOLLAND SWEETENER CO (NL) 2003-04-23 EP claimed
US-20020025549-A1 Synthesis and recovery of aspartame involving enzymatic deformylation step DSM IP ASSETS BV (NL) 2002-02-28 US claimed
EP-1140982-A1 SYNTHESIS AND RECOVERY OF ASPARTAME INVOLVING ENZYMATIC DEFORMYLATION STEP Holland Sweetener Company V.o.F. (NL) 2001-10-10 EP claimed
WO-2000037486-A1 SYNTHESIS AND RECOVERY OF ASPARTAME INVOLVING ENZYMATIC DEFORMYLATION STEP HOLLAND SWEETENER COMPANY V.O.F. (NL) 2000-06-29 WO claimed
EP-1013663-A1 Synthesis and recovery of aspartame involving enzymatic deformylation step Holland Sweetener Company V.O.F. (NL) 2000-06-28 EP claimed
CN-113354556-B C (C)3Chiral ligand H containing symmetrical amide bond3L, preparation method and application 合肥工业大学 2024-07-09 CN disclosed
US-12016842-B2 Methods of using anti-CD79b immunoconjugates GENENTECH, INC. (US) 2024-06-25 US disclosed
US-20240199746-A1 ANTI-AXL ANTIBODIES, ANTIBODY FRAGMENTS AND THEIR IMMUNOCONJUGATES AND USES THEREOF BIOATLA, INC. (US) 2024-06-20 US disclosed
EP-3269737-B1 ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE GENENTECH INC (US) 2024-06-19 EP disclosed
EP-4380978-A1 METHODS OF USING ANTI-CD79B IMMUNOCONJUGATES TO TREAT DIFFUSE LARGE B-CELL LYMPHOMA Genentech, Inc. (US) 2024-06-12 EP disclosed
US-20240115718-A1 METHODS OF USING ANTI-CD79B IMMUNOCONJUGATES TO TREAT DIFFUSE LARGE B-CELL LYMPHOMA GENENTECH, INC. (US) 2024-04-11 US disclosed
US-20240110909-A1 BIOANALYTICAL ANALYSIS OF SITE-SPECIFIC ANTIBODY DRUG CONJUGATES GENENTECH, INC. (US) 2024-04-04 US disclosed
US-6617127-B2 Using N-formylaspartylphenylalanine compound HOLLAND SWEETENER COMPANY, V.O.F. (NL) 2003-09-09 US disclosed
EP-1140982-B1 SYNTHESIS AND RECOVERY OF ASPARTAME INVOLVING ENZYMATIC DEFORMYLATION STEP HOLLAND SWEETENER CO (NL) 2003-04-23 EP disclosed
WO-2002048312-A2 BACKBONE CYCLIZED INHIBITORS OF HEAT SHOCK PROTEINS PEPTOR LTD. (IL) 2002-06-20 WO disclosed
US-20020025549-A1 Synthesis and recovery of aspartame involving enzymatic deformylation step DSM IP ASSETS BV (NL) 2002-02-28 US disclosed
EP-1140982-A1 SYNTHESIS AND RECOVERY OF ASPARTAME INVOLVING ENZYMATIC DEFORMYLATION STEP Holland Sweetener Company V.o.F. (NL) 2001-10-10 EP disclosed
WO-2000037486-A1 SYNTHESIS AND RECOVERY OF ASPARTAME INVOLVING ENZYMATIC DEFORMYLATION STEP HOLLAND SWEETENER COMPANY V.O.F. (NL) 2000-06-29 WO disclosed
EP-1013663-A1 Synthesis and recovery of aspartame involving enzymatic deformylation step Holland Sweetener Company V.O.F. (NL) 2000-06-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12016842-B2 Methods of using anti-CD79b immunoconjugates CD79B, CD99, BCL6 SLC7A5 2185/4885ALPI 3962/4885PKM 4789/4885
US-20240110909-A1 BIOANALYTICAL ANALYSIS OF SITE-SPECIFIC ANTIBODY DRUG CONJUGATES GUSB, DNPEP, FUCA2 SLC7A5 1025/4885ALPI 670/4885PKM 4562/4885
US-20240115718-A1 METHODS OF USING ANTI-CD79B IMMUNOCONJUGATES TO TREAT DIFFUSE LARGE B-CELL LYMPHOMA CD79B, BCL6, CD99 SLC7A5 2183/4885ALPI 4619/4885PKM 4372/4885
US-20240199746-A1 ANTI-AXL ANTIBODIES, ANTIBODY FRAGMENTS AND THEIR IMMUNOCONJUGATES AND USES THEREOF AXL, CD47, ERBB3 SLC7A5 4509/4885ALPI 3321/4885PKM 4382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.