SCHEMBL21518366

SCHEMBL21518366

CCNCC(C)CS(=O)(=O)O

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
SLC22A6 Q4U2R8 1/20 0.32
GRIA1 P42261 3/20 0.31
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30
HIF1A Q16665 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21623880 1.00 KDM4E (0.34) KDM4ESLC22A6GRIA1LMNAHPGD
SCHEMBL21623896 0.83 ANPEP (0.40) SLC22A6GRIA1
SCHEMBL21518361 0.83 ANPEP (0.40) SLC22A6GRIA1
SCHEMBL14058593 0.82 TSHR (0.41)
SCHEMBL21518400 0.80 ANPEP (0.41) GRIA1
SCHEMBL4143314 0.80 ANPEP (0.45) GRIA1
SCHEMBL11797354 0.79 CYP2C19 (0.34) SLC22A6GRIA1
SCHEMBL21623901 0.79 ANPEP (0.47) GRIA1
SCHEMBL21518423 0.79 ANPEP (0.47) GRIA1
SCHEMBL14603042 0.79 ANPEP (0.47) GRIA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4107198-B1 POLYISOCYANATE PREPARATIONS COVESTRO DEUTSCHLAND AG (DE) 2024-03-13 EP disclosed
EP-3560975-B2 IONICALLY HYDROPHILIZED POLYISOCYANATES AND ANTIOXIDANTS COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-12-06 EP disclosed
EP-3724251-B2 IONICALLY HYDROPHILIZED POLYISOCYANATES, WATER CONTENT COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-11-22 EP disclosed
EP-3851472-B1 IONICALLY HYDROPHILIZED POLYISOCYANATES, WATER CONTENT COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-07 EP disclosed
US-20230080775-A1 POLYISOCYANATE PREPARATIONS COVESTRO DEUTSCHLAND AG (DE) 2023-03-16 US disclosed
EP-4107198-A1 POLYISOCYANATE PREPARATIONS Covestro Deutschland AG (DE) 2022-12-28 EP disclosed
CN-110396165-B Ionically hydrophilicized polyisocyanates and antioxidants 科思创德国股份有限公司 2022-12-06 CN disclosed
CN-112041369-B Ionically hydrophilicized polyisocyanates, water content 科思创知识产权两合公司 2022-11-29 CN disclosed
CN-115066445-A Polyisocyanate formulations 科思创德国股份有限公司 2022-09-16 CN disclosed
CN-113651944-B Ionically hydrophilicized polyisocyanates having improved drying properties 科思创知识产权两合公司 2022-07-15 CN disclosed
CN-112041369-A Ionically hydrophilicized polyisocyanates, water content 科思创知识产权两合公司 2020-12-04 CN disclosed
EP-3724251-A1 IONIC HYDROPHILIZED POLYISOCYANATES, WATER CONTENT Covestro Intellectual Property GmbH & Co. KG (DE) 2020-10-21 EP disclosed
EP-3599255-A1 IONICALLY HYDROPHILIZED POLYISOCYANATES WITH IMPROVED DRYING Covestro Deutschland AG (DE) 2020-01-29 EP disclosed
CN-110396165-A Ionic hydrophilic polyisocyanates and antioxidant COVESTRO DEUTSCHLAND AG 2019-11-01 CN disclosed
CN-110396173-A Ionic hydrophilic polyisocyanates and free radical scavenger and/or peroxide decomposer COVESTRO DEUTSCHLAND AG 2019-11-01 CN disclosed
US-20190330408-A1 IONICALLY HYDROPHILIZED POLYISOCYANATES AND RADICAL SCAVENGERS AND/OR PEROXIDE DECOMPOSERS COVESTRO DEUTSCHLAND AG (DE) 2019-10-31 US disclosed
US-20190330409-A1 IONICALLY HYDROPHILIZED POLYISOCYANATES AND ANTIOXIDANTS COVESTRO DEUTSCHLAND AG (DE) 2019-10-31 US disclosed
EP-3560976-A1 IONICALLY HYDROPHILIZED POLYISOCYANATES AND RADICAL SCAVENGER AND/OR PEROXIDE DECOMPOSITION AGENT Covestro Deutschland AG (DE) 2019-10-30 EP disclosed
EP-3560975-A1 IONICALLY HYDROPHILIZED POLYISOCYANATES AND ANTIOXIDANTS Covestro Deutschland AG (DE) 2019-10-30 EP disclosed
EP-3560974-A1 IONICALLY HYDROPHILIZED POLYISOCYANATES, WATER CONTENT Covestro Deutschland AG (DE) 2019-10-30 EP disclosed