⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21093494 | 0.75 | — | — | |
| SCHEMBL20738332 | 0.74 | — | — | |
| SCHEMBL23475188 | 0.74 | — | — | |
| SCHEMBL19645476 | 0.71 | — | — | |
| SCHEMBL18609082 | 0.70 | — | — | |
| SCHEMBL25555310 | 0.69 | — | — | |
| SCHEMBL19261310 | 0.69 | — | — | |
| SCHEMBL18419801 | 0.69 | — | — | |
| SCHEMBL18431877 | 0.67 | — | — | |
| SCHEMBL20738165 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192666-A1 | PIPERAZINE INDAZOLE GLUCOCORTICOID RECEPTOR ANTAGONISTS | CORCEPT THERAPEUTICS INCORPORATED | 2023-06-22 | — | — | US | disclosed |
| US-10457683-B2 | Aryl hydrocarbon receptor antagonists and uses thereof | Magenta Therapeutics Inc. (US) | 2019-10-29 | — | — | US | disclosed |