⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21524622 | 0.82 | — | — | |
| SCHEMBL2680263 | 0.73 | — | — | |
| SCHEMBL764212 | 0.73 | — | — | |
| SCHEMBL9285404 | 0.71 | — | — | |
| SCHEMBL13872397 | 0.71 | CYP19A1 (0.42) | — | |
| SCHEMBL19830214 | 0.71 | — | — | |
| SCHEMBL1685855 | 0.71 | — | — | |
| SCHEMBL19478198 | 0.71 | — | — | |
| Ammonia Solution, Strong SCHEMBL28483640 | 0.70 | CYP19A1 (0.41) | — | |
| SCHEMBL11521784 | 0.69 | CYP19A1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10456392-B2 | Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators | CORCEPT THERAPEUTICS, INC. (US) | 2019-10-29 | — | — | US | disclosed |