Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21525307 | 0.88 | IDH1 (0.74) | IDH1 | |
| SCHEMBL21525259 | 0.85 | IDH1 (0.71) | IDH1 | |
| SCHEMBL17601257 | 0.84 | IDH1 (0.74) | IDH1 | |
| SCHEMBL17601478 | 0.84 | IDH1 (0.82) | IDH1 | |
| SCHEMBL21525258 | 0.83 | IDH1 (0.70) | IDH1 | |
| SCHEMBL17601039 | 0.83 | IDH1 (1.00) | IDH1 | |
| SCHEMBL17601041 | 0.83 | IDH1 (1.00) | IDH1 | |
| SCHEMBL20559996 | 0.83 | IDH1 (0.49) | IDH1 | |
| SCHEMBL17601200 | 0.83 | IDH1 (0.77) | IDH1 | |
| SCHEMBL21525362 | 0.82 | IDH1 (0.70) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3194383-B1 | QUINOLINONE PYRIMIDINES COMPOSITIONS AS MUTANT-ISOCITRATE DEHYDROGENASE INHIBITORS | FORMA THERAPEUTICS INC (US) | 2019-11-06 | — | — | EP | claimed |