Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2148791 | 0.91 | MTOR (0.75) | MTOR | |
| SCHEMBL18156607 | 0.89 | MTOR (0.69) | MTOR | |
| SCHEMBL2181854 | 0.87 | MTOR (0.69) | MTOR | |
| SCHEMBL18142939 | 0.85 | MTOR (0.84) | MTOR | |
| SCHEMBL13718899 | 0.81 | MTOR (0.56) | MTOR | |
| SCHEMBL13718507 | 0.81 | MTOR (0.81) | MTOR | |
| SCHEMBL2148703 | 0.81 | MTOR (0.85) | MTOR | |
| SCHEMBL18142956 | 0.81 | MTOR (0.73) | MTOR | |
| SCHEMBL17747079 | 0.81 | MTOR (0.76) | MTOR | |
| SCHEMBL18142963 | 0.81 | MTOR (0.83) | MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519102-B1 | NOVEL PYRIMIDINE COMPOUNDS AS mTOR AND PI3K INHIBITORS | DEV CENTER BIOTECHNOLOGY (TW) | 2016-10-19 | — | — | EP | claimed |
| EP-2519102-B1 | NOVEL PYRIMIDINE COMPOUNDS AS mTOR AND PI3K INHIBITORS | DEV CENTER BIOTECHNOLOGY (TW) | 2016-10-19 | — | — | EP | disclosed |
| EP-2519102-A2 | NOVEL PYRIMIDINE COMPOUNDS AS mTOR AND PI3K INHIBITORS | Development Center For Biotechnology (TW) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011080568-A2 | NOVEL PYRIMIDINE COMPOUNDS AS MTOR AND P13K INHIBITORS | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2011-07-07 | — | — | WO | disclosed |