SCHEMBL21531916

SCHEMBL21531916

C=C(C)CC[C@@H](N)Cc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.55
ANPEP P15144 1/20 0.48
ALPI P09923 1/20 0.47
PKM P14618 1/20 0.47
PTGS1 P23219 1/20 0.47
XIAP P98170 1/20 0.47
SLC7A5 Q01650 1/20 0.47
SLC6A2 P23975 2/20 0.47
TAAR1 Q96RJ0 2/20 0.47
MAOA P21397 1/20 0.47
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47
SIGMAR1 Q99720 1/20 0.47
CYP2A6 P11509 1/20 0.47
ADORA2A P29274 1/20 0.47
ADORA1 P30542 1/20 0.47
SLC15A1 P46059 1/20 0.45
CYP2D6 P10635 1/20 0.44
MMP2 P08253 2/20 0.44
CSNK1E P49674 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21469872 1.00 EPHX1 (0.55) EPHX1ANPEPALPIPKMPTGS1
SCHEMBL21531932 0.84 EPHX1 (0.57) EPHX1ANPEPALPIPKMPTGS1
SCHEMBL21469939 0.84 EPHX1 (0.57) EPHX1ANPEPALPIPKMPTGS1
SCHEMBL21531941 0.84 EPHX1 (0.57) EPHX1ANPEPALPIPKMPTGS1
SCHEMBL22783136 0.83 EPHX1 (0.52) EPHX1ANPEPALPIPKMPTGS1
SCHEMBL15638183 0.82 ALPI (0.56) EPHX1ANPEPALPIPKMPTGS1
SCHEMBL20718005 0.82 ALPI (0.56) EPHX1ANPEPALPIPKMPTGS1
SCHEMBL21823230 0.81 EPHX1 (0.59) EPHX1ANPEPALPIPKMPTGS1
SCHEMBL18034348 0.79 EPHX1 (0.52) EPHX1ANPEPALPIPKMPTGS1
SCHEMBL2736189 0.78 EPHX1 (0.80) EPHX1ANPEPALPIPKMPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2445489-B1 COMPOSITIONS FOR TREATING DRUG ADDICTION AND IMPROVING ADDICTION-RELATED BEHAVIOR SK BIOPHARMACEUTICALS CO LTD (KR) 2019-10-30 EP disclosed