⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628486 | 0.85 | — | — | |
| SCHEMBL26564954 | 0.77 | — | — | |
| SCHEMBL1629839 | 0.75 | — | — | |
| SCHEMBL16837538 | 0.75 | — | — | |
| SCHEMBL12046862 | 0.71 | — | — | |
| SCHEMBL2628487 | 0.68 | EPHX1 (0.30) | — | |
| SCHEMBL20808119 | 0.67 | — | — | |
| SCHEMBL11989436 | 0.67 | — | — | |
| SCHEMBL13680341 | 0.64 | — | — | |
| SCHEMBL25094680 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787430-B2 | Hemoglobin modifier compounds and uses thereof | FRONTHERA U.S. PHARMACEUTICALS LLC (US) | 2020-09-29 | — | — | US | disclosed |
| US-20190330181-A1 | HEMOGLOBIN MODIFIER COMPOUNDS AND USES THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2019-10-31 | — | — | US | disclosed |