⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21532963 | 0.87 | CHRM2 (0.32) | — | |
| SCHEMBL21532962 | 0.78 | CHRM2 (0.32) | — | |
| SCHEMBL13994794 | 0.76 | — | — | |
| SCHEMBL14550227 | 0.74 | CHRM2 (0.32) | — | |
| SCHEMBL24066647 | 0.70 | HSP90AA1 (0.32) | — | |
| SCHEMBL27393498 | 0.69 | — | — | |
| SCHEMBL29324738 | 0.67 | HSP90AA1 (0.31) | — | |
| SCHEMBL13117939 | 0.67 | HSP90AA1 (0.31) | — | |
| SCHEMBL29324736 | 0.67 | HSP90AA1 (0.31) | — | |
| SCHEMBL24066681 | 0.65 | HSP90AA1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662182-B2 | Microbiocidal thiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-26 | — | — | US | disclosed |
| US-20190330168-A1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-31 | — | — | US | disclosed |